https://doi.org/10.32067/GIE.2021.35.01.01

Effects of mineral trioxide aggregate and platelet-rich fibrin on histological results of direct pulp capping in dogs

Vol. 35 No. 1 (2021)
Submitted: 3 June 2020
Accepted: 5 October 2020
Published: 14 January 2021
dental pulp capping, platelet-rich fibrin, mineral trioxide aggregate
Abstract Views: 1353
PDF: 732
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Authors

Bahareh Aghamohammadi Ameghani
https://orcid.org/0000-0002-0384-0721
Restorative Dentistry Department, Dental School, Birjand University of Medical Sciences, Brjand, Iran, Islamic Republic of.
Azin Tavakoli
Department of clinical sciences, faculty of veterinary medicine, Islamic Azad University, Garmsar branch, Garmsar, Iran, Islamic Republic of.
Masumeh Hasani Tabatabaei
Restorative Dentistry Department, School of dentistry, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
Sara Valizadeh
valizadeh_s@sina.tums.ac.ir
https://orcid.org/0000-0003-0383-7722
Dental Research Center, Dentistry Research Institute, Tehran University of medical Science, Tehran, Iran, Islamic Republic of.

Aim: This study aimed to compare the effects of mineral trioxide aggregate (MTA) and platelet-rich fibrin (PRF) on histological results of direct pulp capping (DPC) in dogs.

Methodology: In this animal study, 36 class V cavities were prepared in the incisors of adult healthy mixed-breed dogs. The teeth were then randomly divided into three groups. No material was placed in the control teeth. MTA and PRF were placed on the exposure site in groups 2 and 3, respectively. After 2 months, the teeth were extracted under general anesthesia and were histological analyzed regarding inflammation, calcified bridge formation and necrosis. Data were analyzed using non-parametric Kruskal-Wallis test. Pairwise comparisons were made using the Mann-Whitney U test.

Results: There are no statistically significant differences in terms of pulp inflammation, dentinal bridge formation and necrosis among the treatment groups capping with MTA and PRF. (P Value >0.05), however, PRF and MTA were the same in all parameters, these groups were both significantly superior to the control group.

Conclusion: Within the limitations of this study, PRF can be used for DPC as an alternative to MTA.

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How to Cite

Aghamohammadi Ameghani, B. ., Tavakoli, A., Hasani Tabatabaei, M., & Valizadeh, S. (2021). Effects of mineral trioxide aggregate and platelet-rich fibrin on histological results of direct pulp capping in dogs. Giornale Italiano Di Endodonzia, 35(1). https://doi.org/10.32067/GIE.2021.35.01.01
Copyright (c) 2021 Bahareh Aghamohammadi Ameghani, Azin Tavakoli, Masumeh Hasani Tabatabaei, Sara Valizadeh Creative Commons License

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