Effects of mineral trioxide aggregate and platelet-rich fibrin on histological results of direct pulp capping in dogs

  • Bahareh Aghamohammadi Ameghani Restorative Dentistry Department, Dental School, Birjand University of Medical Sciences, Brjand, Iran, Islamic Republic of. https://orcid.org/0000-0002-0384-0721
  • Azin Tavakoli Department of clinical sciences, faculty of veterinary medicine, islamic azad university, Garmsar branch, Garmsar, Iran, Islamic Republic of.
  • Masumeh Hasani Tabatabaei Restorative Dentistry Department, School of dentistry, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Sara Valizadeh | valizadeh_s@sina.tums.ac.ir Dental Research Center, Dentistry Research Institute, Tehran University of medical Science, Tehran, Iran, Islamic Republic of. https://orcid.org/0000-0003-0383-7722

Abstract

Aim: This study aimed to compare the effects of mineral trioxide aggregate (MTA) and platelet-rich fibrin (PRF) on histological results of direct pulp capping (DPC) in dogs.

Methodology: In this animal study, 36 class V cavities were prepared in the incisors of adult healthy mixed-breed dogs. The teeth were then randomly divided into three groups. No material was placed in the control teeth. MTA and PRF were placed on the exposure site in groups 2 and 3, respectively. After 2 months, the teeth were extracted under general anesthesia and were histological analyzed regarding inflammation, calcified bridge formation and necrosis. Data were analyzed using non-parametric Kruskal-Wallis test. Pairwise comparisons were made using the Mann-Whitney U test.

Results: There are no statistically significant differences in terms of pulp inflammation, dentinal bridge formation and necrosis among the treatment groups capping with MTA and PRF. (P Value >0.05), however, PRF and MTA were the same in all parameters, these groups were both significantly superior to the control group.

Conclusion: Within the limitations of this study, PRF can be used for DPC as an alternative to MTA.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2021-01-14
Info
Issue
Section
Early View
Keywords:
dental pulp capping, platelet-rich fibrin, mineral trioxide aggregate
Statistics
  • Abstract views: 3

  • PDF: 5
How to Cite
Aghamohammadi Ameghani, B., Tavakoli, A., Hasani Tabatabaei, M., & Valizadeh, S. (2021). Effects of mineral trioxide aggregate and platelet-rich fibrin on histological results of direct pulp capping in dogs. Giornale Italiano Di Endodonzia, 34(2). https://doi.org/10.32067/10.32067/GIE.2021.35.01.01