Influence of sodium hypochlorite and chlorexidine on the dynamic cyclic fatigue resistance of XP-Endo Finisher instruments


Submitted: 11 July 2020
Accepted: 13 October 2020
Published: 8 February 2021
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Aim: This study evaluated the cyclic fatigue resistance of XP-Endo Finisher (XPF), associated with two different irrigation solutions: sodium hypochlorite 6% (NaOCl) or chlorhexidine digluconate gel 2% (CHX) in a dynamic model. The null hypothesis tested was that there was no statistically significant difference.

Methodology: 30 new files were divided into three groups (n=10) based on the irrigation solution used. Group 1: XPF using CHX as an irrigation solution; Group 2: XPF using NaOCl as an irrigation solution; Group 3 (control group): XPF using lubricating oil (LO). The artificial canal was manufactured measuring 1.5 mm wide, 20 mm long, and 3.5 mm deep with a straight cervical segment measuring 14.29 mm. A curved apical segment 4.71 mm with 3 mm radius and 90° of curvature and an ending with straight apical portion measuring 1 mm long. Resistance to cyclic fatigue was determined by recording time to fracture, and the file surface was examined under scanning electron microscopy.

Results: Data were tabulated and subjected to statistical analysis of variance. Student-Newman-Keuls test for multiple comparisons, with a significance level of 5%. The average time took for file fracture was 306.7 seconds for 2% chlorhexidine and 67,6 for 6% sodium hypochlorite. 2% CHX was significantly different from the NaOCl and LO groups (P< .001).

Conclusions: XPF presented the best results of fracture time and the number of cycles to fracture when used along with 2% chlorhexidine in canals with severe apical curvature, and there was no statistical difference in fragment size.


Medeiros Junior, E., Limoeiro, A. G., Tanomaro, A., Soares, A., Campos, G., Mohara, N., Martins, W., Campos, D., & Frozoni, M. (2021). Influence of sodium hypochlorite and chlorexidine on the dynamic cyclic fatigue resistance of XP-Endo Finisher instruments. Giornale Italiano Di Endodonzia, 35(1). https://doi.org/10.32067/GIE.2021.35.01.06

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